Intestinal microbiota and dysbiosis in celiac disease
نویسندگان
چکیده
Celiac disease is a chronic immune-mediated caused by dietary gluten in genetically predisposed individuals. Dysbiotic changes the intestinal microbiota contribute to loss of tolerance and an increase permeability barrier, thus contributing pathogenesis celiac disease. Taxonomic dysbiosis characterized decrease probiotic (anti-inflammatory) bacteria such as Bifidobacterium spp., Lactobacillus spp. Faecalibacterium prausnitzii proinflammatory Bacteroides Escherichia coli, Staphylococcus Functional (metabolic) reduced short-chain fatty acids, especially butyrate, feces significant microbial metabolites blood urine patients with The study functional activity will novel therapeutic approaches management
منابع مشابه
Intestinal microbiota and probiotics in celiac disease.
Celiac disease (CD) is a common chronic autoimmune enteropathy caused by gluten intake. To date, the only therapy for CD is the complete exclusion of dietary sources of grains and any food containing gluten. It has been hypothesized that the intestinal microbiota is somehow involved in CD. For this reason, probiotics are appearing as an interesting adjuvant in the dietetic management of CD. Thi...
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ژورنال
عنوان ژورنال: ?????????? ??????? ????????????? ? ?????????
سال: 2021
ISSN: ['2500-2228', '1027-4065']
DOI: https://doi.org/10.21508/1027-4065-2021-66-2-116-122